http://dspace.bsuedu.ru/handle/123456789/46367
Название: | Endothelioprotective property of the combination of the thioctic acid and rosuvastatin shown in the endothelial dysfunction models |
Авторы: | Molchanova, O. V. Pokrovskaya, T. G. Povetkin, S. V. Reznikov, K. M. |
Ключевые слова: | medicine pharmacology endothelial dysfunction L-NAME thioctic acid rosuvastatin nitric oxide oxidative stress ovarioectomy |
Дата публикации: | 2016 |
Библиографическое описание: | Endothelioprotective property of the combination of the thioctic acid and rosuvastatin shown in the endothelial dysfunction models / O.V. Molchanova [et al.] // Research Result: Pharmacology and Clinical Pharmacology. - 2016. - Vol. 2, № 1(2).- P. 9-15. - Doi: 10.18413/2313-8971-2016-2-1-9-15. - Refer.: p. 14-15. |
Краткий осмотр (реферат): | During the experiment, the modeling of endothelial dysfunction of male rats was performed by intraperitoneal administration of L-NAME at a dose of 25 mg/kg for 7 days, and the same of female rats was performed by bilateral ovarioectomy and further intraperitoneal administration of L-NAME at a dose of 25 mg/kg for 7. The deficiency of nitric oxide as a result of the NO-synthase blockade was accompanied by the impairment of the endotheliumdependent and independent vasodilatation estimated in the pharmacological tests, which was expressed in the increasing coefficient of endothelial dysfunction |
URI (Унифицированный идентификатор ресурса): | http://dspace.bsu.edu.ru/handle/123456789/46367 |
Располагается в коллекциях: | Vol. 2, № 1 |
Файл | Описание | Размер | Формат | |
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Pokrovskaya_Endothelioprotective.pdf | 1.09 MB | Adobe PDF | Просмотреть/Открыть |
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